Prx6 Click the buttons to change the display
Prx6 is a 1-Cys Prx.  When oxidized the CP will form a disulfide bond with another molecule, such as GSH.  There is no CR.

Colored by group.  Cys47, on α2, is displayed in the sulfinic oxidation state (-SO2H) with CPK colors.

Shown in backbone view.  His26, Ser32, and Asp140 are the catalytic residues for the PLA2 activity of Prx6.
Cys47 is red.
His26 is green.
Ser32 is blue.
Asp140 is purple.


Kim, K. H., Lee, W., and Kim, E. E.
Crystal structures of human peroxiredoxin 6 in different oxidation states.
Biochemical and Biophysical Research Communications (2016) 477, 717–722. (PubMed)

5b6n (PDB)

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